Encased: A Sci-Fi Post-Apocalyptic RPG, is an isometric turn-based RPG developed by Dark Crystal Games and inspired by games like Fallout and Wasteland as well as Soviet-era sci-fi novel Roadside Picnic.

This is included in the January Humble Choice and looks really interesting. Love the game videos included on Steam, especially the advert style invitation to join the dome. And it looks like it's got a lot of replayability based on how you create your character and the job role you take changing the game outcomes.
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